Common Sleepiness, Blurred vision, Increased heart rate, Dryness in mouth, Constipation, Weight gain, Difficulty in urination, Orthostatic hypotension (sudden lowering of blood pressure on standing).

Expert advice for Pryl Tablet SR
The main dose should be taken at night as this drug may produce drowsiness or sleepiness. It can take 4 to 6 weeks for Pryl to start working. You should continue the treatment for at least 6 months after you feel better to stop depression from coming back. If your doctor asks you to stop Pryl, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Avoid driving or operating machinery as it may decrease alertness. Avoid consuming alcohol when taking the Pryl, as it may cause excessive drowsiness and calmness. The addiction/dependence potential of Pryl is very less. It may be extremely dangerous in overdose.

Q. Is Pryl safe?
Pryl is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Pryl a steroid?
No, Pryl is not a steroid. It belongs to class of medication called as tricyclic antidepressant.

Q. Can I take Pryl with Betahistine?
Pryl has not been clinically studied when used along with Betahistine. So there are no reports of any drug-drug interactions or harmful effects when these are used together.